.. currentmodule:: brian

.. _example-electrophysiology_compensation_ex1:

Example: compensation_ex1 (electrophysiology)
=============================================

Example of L^p electrode compensation method. Requires binary files 
"current.npy" and "rawtrace.npy".

    Rossant et al., "A calibration-free electrode compensation method"
    J. Neurophysiol 2012

::

    import os
    
    from brian import *
    import numpy as np
    from brian.library.electrophysiology import *
    
    working_dir = os.path.dirname(__file__)
    
    # load data
    dt = 0.1*ms
    current = np.load(os.path.join(working_dir, "current.npy"))  # 10000-long vector, 1s duration
    rawtrace = np.load(os.path.join(working_dir, "trace.npy"))  # 10000-long vector, 1s duration
    t = linspace(0., 1., len(current))
    
    # launch compensation
    r = Lp_compensate(current, rawtrace, dt, p=1.0, full=True)
    
    # print best parameters
    print "Best parameters: R, tau, Vr, Re, taue:"
    print r["params"]
    
    # plot traces
    subplot(211)
    plot(t, current, 'k')
    
    subplot(212)
    plot(t, rawtrace, 'k')  # raw trace
    plot(t, r["Vfull"], 'b')  # full model trace (neuron and electrode)
    plot(t, r["Vcompensated"], 'g')  # compensated trace
    
    show()